Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185997 | 0.80 | KDM4E (0.45) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8187531 | 0.79 | KDM4E (0.34) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8191383 | 0.79 | HTR2A (0.34) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8190726 | 0.78 | KDM4E (0.35) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8191815 | 0.78 | KDM4E (0.33) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8185648 | 0.78 | KDM4E (0.37) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8185193 | 0.78 | KDM4E (0.33) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8190629 | 0.77 | POLB (0.39) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8176836 | 0.77 | KDM4E (0.32) | ALDH1A1POLBL3MBTL1NPC1RAB9A | |
| SCHEMBL8186151 | 0.77 | KDM4E (0.34) | ALDH1A1POLBL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057330-A | USEFUL FOR THE PREVENTION AND TREATMENT OF A RESPIRATORY DISEASES REPRESENTED BY ASTHMA | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-05-02 | — | — | US | disclosed |