Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18142931 | 0.99 | SMN1; SMN2 (0.62) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL2240238 | 0.95 | SMN1; SMN2 (0.63) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL2240242 | 0.95 | SMN1; SMN2 (0.63) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL1769623 | 0.89 | EPHX2 (0.70) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL1769619 | 0.89 | EPHX2 (0.70) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8177454 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8177140 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL8177757 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL24011624 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 | |
| SCHEMBL22170879 | 0.81 | SMN1; SMN2 (0.70) | SMN1; SMN2EPHX2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051584-A | Hemoregulatory compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2000-04-18 | — | — | US | disclosed |