⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785870 | 1.00 | — | — | |
| SCHEMBL7795417 | 1.00 | — | — | |
| SCHEMBL7791689 | 0.97 | — | — | |
| SCHEMBL11680495 | 0.91 | — | — | |
| SCHEMBL11683143 | 0.87 | — | — | |
| SCHEMBL28599004 | 0.85 | — | — | |
| SCHEMBL2293105 | 0.85 | — | — | |
| SCHEMBL19131319 | 0.80 | — | — | |
| SCHEMBL9766362 | 0.78 | ESR1 (0.32) | — | |
| SCHEMBL18675702 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028157-A | Vinyl-containing silanol-terminated silicone compositions for treatment of fillers | GENERAL ELECTRIC COMPANY (US) | 2000-02-22 | — | — | US | disclosed |
| US-5674935-A | IN SITU TREATMENT OF REINFORCING SILICA FILLER TO PROMOTE CROSSLINKING IN A VULCANIZABLE SILICONE OR FLUOROSILICONE ELASTOMER | GENERAL ELECTRIC COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0491510-A2 | Vinyl-containing silanol-terminated silicone compositions | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |