Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.89 |
| ▸ | LTA4H | P09960 | 4/20 | 0.77 |
| ▸ | RARB | P10826 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28107978 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL27889979 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL7796805 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL12633727 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL9225728 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL7736934 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL5688520 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL10536480 | 1.00 | NR5A1 (0.89) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL7110214 | 0.98 | NR5A1 (0.85) | NR5A1LTA4HRARBCYP3A4CYP2D6 | |
| SCHEMBL1834632 | 0.94 | NR5A1 (1.00) | NR5A1LTA4HRARBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| EP-0520281-B1 | Optical element for generating short wave laser light | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0520281-A2 | Optical element for generating short wave laser light | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-30 | — | — | EP | disclosed |
| EP-0152217-B1 | LIQUID CRYSTALLINE CARBONIC ACID ESTERS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4647398-A | Liquid-crystalline carbonic acid esters and liquid crystal compositions containing same | CHISSO CORPORATION (JP) | 1987-03-03 | — | — | US | disclosed |
| EP-0152217-A2 | Liquid crystalline carbonic acid esters and liquid crystal compositions containing them | Chisso Corporation (JP) | 1985-08-21 | — | — | EP | disclosed |