Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994897 | 0.87 | HTR2C (0.65) | HTR2CHTR2BSMN1; SMN2GFERCDK2 | |
| SCHEMBL1128542 | 0.81 | GFER (0.63) | HTR2CHTR2BSMN1; SMN2GFERHDAC3 | |
| SCHEMBL26812415 | 0.79 | GFER (0.60) | HTR2CHTR2BSMN1; SMN2GFERHDAC3 | |
| SCHEMBL4773205 | 0.79 | HTR2C (1.00) | HTR2CHTR2BPNMT | |
| SCHEMBL1806454 | 0.78 | GFER (0.59) | HTR2CHTR2BSMN1; SMN2GFERHDAC3 | |
| SCHEMBL4230983 | 0.78 | CA1 (0.61) | SMN1; SMN2GFERHDAC3HDAC4HDAC1 | |
| SCHEMBL30664965 | 0.78 | CA1 (0.61) | SMN1; SMN2GFERHDAC3HDAC4HDAC1 | |
| SCHEMBL27947100 | 0.78 | SMN1; SMN2 (0.63) | HTR2CHTR2BSMN1; SMN2GFERHDAC3 | |
| SCHEMBL31591380 | 0.77 | SMN1; SMN2 (0.71) | HTR2CHTR2BSMN1; SMN2GFERCDK2 | |
| SCHEMBL1818147 | 0.77 | SMN1; SMN2 (0.71) | HTR2CHTR2BSMN1; SMN2GFERCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000076966-A2 | INDOLINYLAMIDE DERIVATIVES AND THE USE THEREOF AS ANTIVIRAL DRUGS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-21 | — | — | WO | disclosed |