SCHEMBL8181554

SCHEMBL8181554

CCCCCC[C@@H](C)Oc1ccc(-c2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.46
KCNH2 Q12809 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
STS P08842 6/20 0.44
ESR1 P03372 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
ESR2 Q92731 1/20 0.44
CA14 Q9ULX7 1/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8181558 1.00 RARB (0.46) RARBKCNH2HRH3STSESR1
SCHEMBL13152977 0.88 ESR1 (0.57) STSESR1NPC1MAPTRAB9A
SCHEMBL8532922 0.85 RARB (0.63) RARBMAPTALDH1A1TSHR
SCHEMBL8082284 0.85 RARB (0.63) RARBMAPTALDH1A1TSHR
SCHEMBL14038265 0.85 RARB (0.49) RARBMAPTRAB9AALDH1A1LMNA
SCHEMBL8082310 0.85 RARB (0.63) RARBMAPTALDH1A1TSHR
SCHEMBL8194653 0.85 RARB (0.63) RARBMAPTALDH1A1TSHR
SCHEMBL9351233 0.84 RARB (0.48) RARBMAPTALDH1A1TSHR
Hydrochloric Acid SCHEMBL10455057 0.84 RARB (0.62) RARBMAPTALDH1A1TSHR
SCHEMBL10455055 0.84 RARB (0.48) RARBMAPTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143208-A Optical element and compounds used in its manufacture ROLIC AG (CH) 2000-11-07 US disclosed
US-5335303-A Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure HOFFMANN-LA ROCHE INC. (US) 1994-08-02 US disclosed