Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171293 | 0.94 | CYSLTR2 (0.83) | CYSLTR2CYSLTR1 | |
| SCHEMBL8183521 | 0.91 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL8171382 | 0.88 | CYSLTR1 (0.83) | CYSLTR2CYSLTR1 | |
| SCHEMBL9015177 | 0.85 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1 | |
| SCHEMBL8178443 | 0.85 | CYSLTR2 (0.82) | CYSLTR2CYSLTR1 | |
| SCHEMBL8179248 | 0.85 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL8188934 | 0.83 | CYSLTR2 (0.85) | CYSLTR2CYSLTR1 | |
| SCHEMBL8180915 | 0.83 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL8184334 | 0.82 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL8179951 | 0.81 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643045-B1 | Quinoline derivatives as leukotriene antagonists | NOVARTIS AG (CH) | 2000-03-08 | — | — | EP | disclosed |
| US-5508408-A | LEUKOTRIENE ANTAGONISTS | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0643045-A1 | Quinoline derivatives as leukoriene antagonists | CIBA-GEIGY AG (CH) | 1995-03-15 | — | — | EP | disclosed |