Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182644 | 1.00 | AKR1B1 (0.62) | AKR1B1CA9PTPN22 | |
| SCHEMBL7250592 | 0.87 | PTPN12 (0.59) | PTPN22 | |
| SCHEMBL7250589 | 0.87 | PTPN12 (0.59) | PTPN22 | |
| SCHEMBL20534339 | 0.83 | AKR1B1 (0.68) | AKR1B1CA9PTPN22 | |
| SCHEMBL20534338 | 0.83 | AKR1B1 (0.68) | AKR1B1CA9PTPN22 | |
| SCHEMBL20534585 | 0.83 | AKR1B1 (0.71) | AKR1B1CA9 | |
| SCHEMBL13851456 | 0.83 | AKR1B1 (0.71) | AKR1B1CA9 | |
| SCHEMBL13401689 | 0.83 | AKR1B1 (0.71) | AKR1B1CA9 | |
| SCHEMBL21773419 | 0.78 | AKR1B1 (0.61) | AKR1B1CA9 | |
| SCHEMBL20534556 | 0.78 | AKR1B1 (0.61) | AKR1B1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |