Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665584 | 0.85 | CA1 (0.43) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7665563 | 0.85 | CA12 (0.33) | CA1CA2MEN1KMT2A | |
| SCHEMBL7660817 | 0.82 | CA1 (0.42) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7660921 | 0.82 | CA1 (0.40) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7667139 | 0.80 | CA1 (0.40) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7662784 | 0.80 | CA1 (0.40) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7666039 | 0.80 | CA1 (0.43) | CA1CA2KDM4EMEN1THRB | |
| SCHEMBL7659078 | 0.76 | — | — | |
| SCHEMBL7668820 | 0.76 | — | — | |
| SCHEMBL7659060 | 0.76 | CA1 (0.40) | CA1CA2KDM4EMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021430-A1 | FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| US-6051571-A | NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-6040444-A | Process for preparing furan nitrone compounds | CENTAUR PHARMACEUTICALS, INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5942507-A | REAGANTS FOR DETECTION FREE RADICALS | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998003496-A1 | FURAN NITRONE COMPOUNDS | CENTAUR PHARMACEUTICALS, INC. (US) | 1998-01-29 | — | — | WO | disclosed |