Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.86 |
| ▸ | HTR2C | P28335 | 1/20 | 0.86 |
| ▸ | MAPT | P10636 | 3/20 | 0.83 |
| ▸ | PPARG | P37231 | 2/20 | 0.83 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.83 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.83 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.83 |
| ▸ | ALB | P02768 | 1/20 | 0.83 |
| ▸ | PGR | P06401 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | DAO | P14920 | 1/20 | 0.71 |
| ▸ | SNCA | P37840 | 1/20 | 0.71 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.71 |
| ▸ | APEX1 | P27695 | 3/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460326 | 1.00 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9593004 | 1.00 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Trifluoroacetic Acid SCHEMBL10377498 | 0.95 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| Trifluoroacetic Acid SCHEMBL10377500 | 0.95 | NR1I2 (0.79) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9371771 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10761869 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL16118738 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL10554693 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5679457 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5679450 | 0.93 | NR1I2 (0.86) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997466-A1 | Novel antimicrobial lactam-quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5656623-A | BACTERICIDES; ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-08-12 | — | — | US | disclosed |
| US-5648346-A | Antimicrobial carbacephem-quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5646139-A | TREATING AND PREVENTING INFECTION | THE PROCTER & GAMBLE COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5637580-A | ANTIBIOTICS | THE PROCTER & GAMBLE COMPANY (US) | 1997-06-10 | — | — | US | disclosed |