Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185389 | 1.00 | TSHR (0.46) | TSHRACHEALDH1A1CYP3A4GAA | |
| SCHEMBL8180555 | 1.00 | TSHR (0.46) | TSHRACHEALDH1A1CYP3A4GAA | |
| SCHEMBL8178269 | 1.00 | TSHR (0.46) | TSHRACHEALDH1A1CYP3A4GAA | |
| SCHEMBL8187484 | 1.00 | TSHR (0.46) | TSHRACHEALDH1A1CYP3A4GAA | |
| SCHEMBL1375008 | 0.98 | TSHR (0.42) | TSHRACHEALDH1A1CYP3A4GAA | |
| Ethylene Glycol SCHEMBL2025231 | 0.91 | TSHR (0.44) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL1374276 | 0.91 | TSHR (0.39) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL27571545 | 0.91 | TSHR (0.52) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL8185075 | 0.83 | TSHR (0.46) | TSHRALDH1A1CYP3A4POLBAPEX1 | |
| SCHEMBL9362172 | 0.83 | TSHR (0.46) | TSHRALDH1A1CYP3A4POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143208-A | Optical element and compounds used in its manufacture | ROLIC AG (CH) | 2000-11-07 | — | — | US | disclosed |
| EP-0520281-B1 | Optical element for generating short wave laser light | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| US-5335303-A | Quasi-phased matched optical waveguide frequency conversion element having a ferroelectric liquid crystalline material exhibiting a periodic structure | HOFFMANN-LA ROCHE INC. (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0520281-A2 | Optical element for generating short wave laser light | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-30 | — | — | EP | disclosed |