Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 1.00 |
| ▸ | CXCR3 | P49682 | 8/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185238 | 1.00 | CCR1 (1.00) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8188084 | 1.00 | CCR1 (1.00) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8188088 | 1.00 | CCR1 (1.00) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8184814 | 0.89 | CCR1 (0.79) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8184811 | 0.89 | CCR1 (0.79) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8190112 | 0.88 | CCR1 (1.00) | CCR1CXCR3 | |
| SCHEMBL8190114 | 0.88 | CCR1 (1.00) | CCR1CXCR3 | |
| SCHEMBL8189607 | 0.86 | CCR1 (0.74) | CCR1CXCR3CYP2D6 | |
| SCHEMBL7572767 | 0.86 | CCR1 (0.78) | CCR1CXCR3CYP2D6 | |
| SCHEMBL8189605 | 0.86 | CCR1 (0.74) | CCR1CXCR3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | claimed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | claimed |
| US-6140338-A | FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS | BANYU PHARMACEUTICAL, CO., LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| EP-0916668-A1 | CHEMOKINE RECEPTOR ANTAGONISTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1999-05-19 | — | — | EP | disclosed |