⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933739 | 0.86 | — | — | |
| SCHEMBL11047546 | 0.83 | EPHX1 (0.31) | — | |
| SCHEMBL9832610 | 0.69 | — | — | |
| SCHEMBL11242729 | 0.67 | — | — | |
| SCHEMBL31325979 | 0.67 | — | — | |
| SCHEMBL2047837 | 0.67 | — | — | |
| SCHEMBL5270433 | 0.67 | — | — | |
| SCHEMBL22797 | 0.67 | — | — | |
| SCHEMBL5615220 | 0.67 | EPHX1 (0.42) | — | |
| SCHEMBL7666722 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230430-A | Clean production method of cyclopropane | 九江中天药业有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-108440229-A | A kind of preparation method of anti-AIDS drug big human relations intermediate cyclopropyl acetylene in accordance with the law | 瑞孚信江苏药业股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-105152846-A | Method for efficiently preparing cylopropyl ethylnen | JIUJIANG ZHONGTIAN PHARMACEUTICAL CO LTD | 2015-12-16 | — | — | CN | claimed |
| WO-1999048848-A1 | METHOD TO REDUCE THE AMOUNT OF PHOSPHORUS OXYHALIDES AND DIHALOGENATED PENTENES IN 1,1-DIHALO-1-CYCLOPROPYLETHANES | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-09-30 | — | — | WO | claimed |
| EP-0142769-B1 | TETRAHYDROBENZOTRIAZOLES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-02 | — | — | EP | claimed |
| CN-223945657-U | Precipitation-preventing cyclopropylacetylene synthesis device | 九江中天药业有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-111499486-B | Safe and environment-friendly preparation method of cyclopropylacetylene | 江西伟康生物科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-111233618-B | Method for preparing chloroethylene compounds by using phosgene | 浙江新和成股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114230430-A | Clean production method of cyclopropane | 九江中天药业有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-114230430-A | Clean production method of cyclopropane | 九江中天药业有限公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-111499486-A | Safe and environment-friendly preparation method of cyclopropylacetylene | 江西伟康生物科技有限公司 | 2020-08-07 | — | — | CN | disclosed |
| CN-111233618-A | Method for preparing chloroethylene compounds by using phosgene | 浙江新和成股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| EP-0922686-A1 | Process for the preparation of ethynylcyclopropane | LONZA A.G. (CH) | 1999-06-16 | — | — | EP | disclosed |
| WO-1999014176-A1 | METHOD FOR THE GEMINAL DICHLORINATION OF ALKYL METHYL KETONES | GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) | 1999-03-25 | — | — | WO | disclosed |
| WO-1999007658-A1 | PREPARATION OF GEM-DIHALOALKANES | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999007658-A1 | PREPARATION OF GEM-DIHALOALKANES | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999007657-A1 | EFFICIENT SYNTHESIS OF CYCLOPROPYLACETYLENE | MERCK & CO., INC. (US) | 1999-02-18 | — | — | WO | disclosed |
| WO-1998040333-A1 | IMPROVED PROCESS FOR PREPARING CYCLOPROPYLACETYLENE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-17 | — | — | WO | disclosed |
| EP-0847974-A1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |
| EP-0142769-B1 | TETRAHYDROBENZOTRIAZOLES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-02 | — | — | EP | disclosed |