Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370544 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL7814071 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL8186262 | 0.78 | CA1 (0.38) | SMN1; SMN2CA1CA2ALDH1A1 | |
| SCHEMBL27521633 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL27521634 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL27522067 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL9459932 | 0.75 | CA1 (0.39) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL2828705 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2CA1CA2CA14CA12 | |
| SCHEMBL6669359 | 0.71 | PTGS1 (0.48) | SMN1; SMN2CA1CA2 | |
| SCHEMBL6669356 | 0.71 | PTGS1 (0.48) | SMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090946-A | Process for the preparation of 3-(substituted phenyl)-5-alkylidene-1,3-oxazolidine-2,4-dione derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0812834-A1 | PROCESS FOR THE PREPARATION OF 3-(SUBSTITUTED PHENYL)-5-ALKYLIDENE-1,3-OXAZOLIDINE-2,4-DIONE DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-12-17 | — | — | EP | disclosed |