SCHEMBL8186802

SCHEMBL8186802

CCC(C1CCCCCCC1)N1CCC(NC(=O)C2c3ccccc3Oc3ccccc32)CC1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 19/20 0.64
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8189916 0.86 CCR1 (0.65) CCR1
SCHEMBL8184859 0.86 CCR1 (0.65) CCR1
Iodide SCHEMBL8189418 0.85 CCR1 (0.64) CCR1
SCHEMBL9901319 0.78 CCR1 (0.57) CCR1
SCHEMBL8189356 0.78 CCR1 (1.00) CCR1
SCHEMBL8184988 0.78 CCR1 (1.00) CCR1
SCHEMBL8190177 0.78 CCR1 (1.00) CCR1
SCHEMBL8186702 0.78 CCR1 (1.00) CCR1
SCHEMBL8184860 0.77 CCR1 (0.80) CCR1
SCHEMBL9912181 0.76 CCR1 (0.65) CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140338-A FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS BANYU PHARMACEUTICAL, CO., LTD. (JP) 2000-10-31 US claimed
EP-0916668-A1 CHEMOKINE RECEPTOR ANTAGONISTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-05-19 EP claimed
US-6140338-A FOR TREATING ACUTE INFLAMMATORY DISEASES, CHRONIC INFLAMMATORY DISEASES, ACQUIRED IMMUNE DEFICIENCY SYNDROME, CANCER, ISCHEMIC REFLOW DISORDER AND/OR ARTERIOSCLEROSIS BANYU PHARMACEUTICAL, CO., LTD. (JP) 2000-10-31 US disclosed
EP-0916668-A1 CHEMOKINE RECEPTOR ANTAGONISTS BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-05-19 EP disclosed