Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.64 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.64 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8186886 | 1.00 | PIM1 (0.64) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181612 | 0.99 | PIM1 (0.66) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181608 | 0.99 | PIM1 (0.66) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8188212 | 0.85 | HPGD (0.74) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8188211 | 0.85 | HPGD (0.74) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181424 | 0.84 | PIM1 (0.67) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181421 | 0.84 | PIM1 (0.67) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181806 | 0.84 | PIM1 (0.67) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181804 | 0.84 | PIM1 (0.67) | PIM1PIM2CISD1HPGDMEN1 | |
| SCHEMBL8181583 | 0.83 | PIM1 (0.58) | PIM1PIM2CISD1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018746-A1 | THIAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |