Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.60 |
| ▸ | FNTB | P49356 | 2/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 16/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 16/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8192254 | 0.99 | FNTA (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8189055 | 0.86 | CYP11B1 (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7512747 | 0.82 | CYP11B1 (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8176324 | 0.80 | CYP11B1 (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8183718 | 0.76 | CYP11B1 (0.63) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8124480 | 0.76 | CYP11B1 (0.49) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8388778 | 0.76 | CYP11B1 (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8388781 | 0.76 | CYP11B1 (0.59) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL1949482 | 0.75 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1 | |
| SCHEMBL5891418 | 0.74 | CYP11B1 (0.55) | FNTAFNTBPGGT1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063930-A | Substituted imidazole compounds useful as farnesyl-protein transferase inhibitors | MERCK & CO., INC. (US) | 2000-05-16 | — | — | US | disclosed |