Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826906 | 0.85 | ROCK1 (0.49) | ROCK1ALDH1A1PTGS1KDM4E | |
| SCHEMBL17324820 | 0.83 | ROCK1 (0.51) | ROCK1ALDH1A1PTGS1SMN1; SMN2KDM4E | |
| SCHEMBL27850030 | 0.82 | MAP2K1 (0.48) | ROCK1ALDH1A1PTGS1KDM4EHPGD | |
| SCHEMBL9230948 | 0.81 | NPC1 (0.46) | ROCK1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10751885 | 0.80 | MAPK14 (0.50) | MAPK14ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7915015 | 0.79 | MAPK14 (0.66) | MAPK14ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL17321469 | 0.79 | ROCK1 (0.46) | ROCK1ALDH1A1PTGS1SMN1; SMN2KDM4E | |
| SCHEMBL21412873 | 0.79 | RXFP1 (0.50) | MAPK14ALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21409787 | 0.79 | KDM4C (0.46) | ALDH1A1NPC1HPGDMAPT | |
| SCHEMBL8189919 | 0.73 | NR1H2 (0.49) | MAPK14ALDH1A1SMN1; SMN2POLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019188456-A1 | NOVEL ANTI-TUMOR AGENT | 学校法人 川崎学園 | 2019-10-03 | — | — | WO | disclosed |
| US-6030926-A | AS HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5939559-A | HERBICIDES FROM PYRAZOLE KETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0822187-A1 | PYRAZOLE DERIVATIVES AND HERBICIDES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-02-04 | — | — | EP | disclosed |