Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.45 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187060 | 0.90 | HDAC1 (0.52) | HDAC6HDAC3HDAC8HDAC4MEF2D | |
| SCHEMBL13429151 | 0.88 | HDAC6 (0.46) | HDAC6HDAC3HDAC8HDAC4MEF2D | |
| SCHEMBL8179581 | 0.85 | CA12 (0.44) | HPGD | |
| SCHEMBL8190118 | 0.80 | HDAC1 (0.40) | HDAC6HDAC3HDAC8HDAC4MEF2D | |
| SCHEMBL8182903 | 0.80 | KDM4E (0.37) | HDAC6HDAC3HDAC8HDAC4HDAC1 | |
| SCHEMBL8184323 | 0.80 | CA12 (0.45) | HPGD | |
| SCHEMBL13429156 | 0.78 | HDAC1 (0.52) | HDAC6HDAC3HDAC8HDAC4MEF2D | |
| SCHEMBL13428572 | 0.78 | AKR1C3 (0.44) | GSK3BKDM4EHPGD | |
| SCHEMBL8194299 | 0.78 | KMT2A (0.48) | HDAC6HDAC3HDAC8HDAC4MEF2D | |
| SCHEMBL8182974 | 0.74 | P2RY12 (0.50) | KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075757-A1 | N-HYDROXYACRYLAMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2008-06-26 | — | — | WO | disclosed |