Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194719 | 1.00 | TACR1 (0.84) | TACR1 | |
| SCHEMBL8323699 | 0.93 | TACR1 (0.83) | TACR1 | |
| SCHEMBL8320593 | 0.93 | TACR1 (0.82) | TACR1 | |
| SCHEMBL3373694 | 0.92 | TACR1 (0.81) | TACR1 | |
| SCHEMBL14198247 | 0.92 | TACR1 (0.81) | TACR1 | |
| SCHEMBL8325742 | 0.92 | TACR1 (0.85) | TACR1 | |
| SCHEMBL8325736 | 0.92 | TACR1 (0.85) | TACR1 | |
| Vofopitant SCHEMBL2996010 | 0.92 | TACR1 (1.00) | TACR1 | |
| Vofopitant SCHEMBL8901341 | 0.92 | TACR1 (1.00) | TACR1 | |
| Vofopitant SCHEMBL310338 | 0.92 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020346-A | Piperidine derivatives having tachykinin antagonist activity | GLAXO WELLCOME INC. (US) | 2000-02-01 | — | — | US | claimed |