Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | EIF4E | P06730 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185336 | 0.85 | SLC6A4 (0.41) | SMN1; SMN2ADRA2AADRA2BADRA2CPTPN1 | |
| SCHEMBL8185964 | 0.84 | F2RL1 (0.36) | KDM4CADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL8185111 | 0.80 | BRS3 (0.38) | EIF4EPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL8194804 | 0.78 | PTGDR2 (0.38) | KDM4CADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL8186060 | 0.78 | FNTA (0.44) | — | |
| SCHEMBL8194280 | 0.77 | FNTA (0.40) | — | |
| SCHEMBL8197782 | 0.77 | FNTA (0.40) | — | |
| SCHEMBL8181769 | 0.76 | PPARA (0.38) | EIF4EKDM4CF2RL1BRS3XDH | |
| SCHEMBL6954666 | 0.75 | F2RL1 (0.43) | ADRA2AADRA2BADRA2CF2RL1 | |
| SCHEMBL6487707 | 0.73 | SMN1; SMN2 (0.57) | SMN1; SMN2PTPN11EIF4EPRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999020611-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-04-29 | — | — | WO | disclosed |