SCHEMBL81954

SCHEMBL81954

O=C(OF)C(F)(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8811533 1.00
SCHEMBL7456988 0.91
SCHEMBL23829882 0.82
SCHEMBL4395003 0.80
SCHEMBL8386085 0.77
SCHEMBL14879619 0.77
SCHEMBL28359794 0.76
SCHEMBL2481917 0.76
SCHEMBL7526984 0.76
SCHEMBL17870959 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173076-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2023-06-08 US disclosed
EP-3237435-B1 METABOLICALLY STABLE APELIN ANALOGS IN THE TREATMENT OF DISEASE MEDIATED BY THE APELIN RECEPTOR INST NAT SANTE RECH MED (FR) 2023-05-24 EP disclosed
US-20220073446-A1 Antigen Delivery Vectors and Constructs ALTIMMUNE UK LIMITED (GB) 2022-03-10 US disclosed
US-11066353-B2 Antigen delivery vectors and constructs ALTIMMUNE UK LTD (GB) 2021-07-20 US disclosed
US-20210206817-A1 Metabolically Stable Apelin Analogs in the Treatment of Disease Mediated by the Apelin Receptor INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) 2021-07-08 US disclosed
EP-3472195-B1 METABOLICALLY STABLE SPEXIN PEPTIDE ANALOGS UNIV STRASBOURG (FR) 2021-05-26 EP disclosed
EP-3472191-B1 METABOLICALLY STABLE FLUOROPEPTIDE ANALOGS UNIV STRASBOURG (FR) 2021-05-26 EP disclosed
US-20190328887-A1 METABOLICALLY STABLE PEPTIDE ANALOGS UNIVERSITÉ DE STRASBOURG (FR) 2019-10-31 US disclosed
US-20190135887-A1 METABOLICALLY STABLE SPEXIN PEPTIDE ANALOGS UNIVERSITÉ DE STRASBOURG (FR) 2019-05-09 US disclosed
EP-3472191-A1 METABOLICALLY STABLE PEPTIDE ANALOGS Université de Strasbourg (FR) 2019-04-24 EP disclosed
US-8110540-B2 Antigen delivery vectors and constructs IMMUNE TARGETING SYSTEMS LTD. (GB) 2012-02-07 US disclosed
EP-2374477-A1 Antigen delivery vectors and constructs Immune Targeting Systems (GB) 2011-10-12 EP disclosed
US-20100183708-A1 Antigen Delivery Vectors and Constructs IMMUNE TARGETING SYSTEMS LTD. 2010-07-22 US disclosed
US-20100183650-A1 Antigen Delivery Vectors and Constructs IMMUNE TARGETING SYSTEMS LTD. 2010-07-22 US disclosed
US-7687455-B2 comprising fluorocarbon vector-antigen, immunogens; vaccines, immunotherapy IMMUNE TARGETING SYSTEMS LTD. (GB) 2010-03-30 US disclosed
CN-1980695-A Antigen delivery vectors and constructs IMMUNE TARGETING SYSTEMS (GB) 2007-06-13 CN disclosed
EP-1740207-A2 ANTIGEN DELIVERY VECTORS AND CONSTRUCTS Immune Targeting Systems (GB) 2007-01-10 EP disclosed
US-20060013820-A1 comprising fluorocarbon vector-antigen, immunogens; vaccines, immunotherapy ALTIMMUNE UK LIMITED (GB) 2006-01-19 US disclosed
WO-2005099752-A9 ANTIGEN DELIVERY VECTORS AND CONSTRUCTS IMMUNE TARGETING SYSTEMS (GB) 2005-12-15 WO disclosed
WO-2005099752-A2 ANTIGEN DELIVERY VECTORS AND CONSTRUCTS IMMUNE TARGETING SYSTEMS (GB) 2005-10-27 WO disclosed