Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201256 | 0.89 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL345968 | 0.88 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9494373 | 0.88 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL346937 | 0.88 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5172119 | 0.88 | USP2 (0.72) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL15984354 | 0.88 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL5171904 | 0.87 | USP2 (0.71) | USP2PSEN1PSEN2APH1BNCSTN | |
| Hydrochloric Acid SCHEMBL5171901 | 0.87 | USP2 (0.71) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL346978 | 0.86 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7797653 | 0.86 | USP2 (0.69) | USP2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043278-A | FORMULATION COMPRISING MIXTURE OF BETA-LACTAM ANTIBIOTIC AND PERFLUOROLOWERALKYL DERIVATIVE OF AMINO ACID | ISIS INNOVATION LIMITED (GB) | 2000-03-28 | — | — | US | disclosed |