Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266395 | 0.98 | TSHR (0.67) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL11173057 | 0.93 | TSHR (0.75) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL31578944 | 0.90 | TSHR (0.70) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL11313358 | 0.90 | TSHR (0.70) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL31579008 | 0.90 | TSHR (0.70) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL31578856 | 0.90 | TSHR (0.70) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL3526699 | 0.89 | TSHR (0.50) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL10705661 | 0.89 | TSHR (0.50) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| Hydrochloric Acid SCHEMBL9033471 | 0.88 | TSHR (0.67) | TSHRLMNAALDH1A1EPHX2KMT2A | |
| SCHEMBL31578986 | 0.87 | TSHR (0.74) | TSHRLMNAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013823-A | AS CHEMICAL INTERMEDIATES; UTROTONIC AGENTS, BRONCHODIALATORS | NEW PHARMA INTERNATIONAL CORP. (UY) | 2000-01-11 | — | — | US | disclosed |
| US-5817694-A | OXYTOCICS | NEW PHARMA INTERNATIONAL CORP. (UY) | 1998-10-06 | — | — | US | disclosed |
| EP-0574185-B1 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORP (UY) | 1997-09-03 | — | — | EP | disclosed |
| EP-0574185-A2 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORPORATION (UY) | 1993-12-15 | — | — | EP | disclosed |
| US-3980700-A | Prostaglandin intermediates and optically active isomers thereof | G. D. SEARLE & CO. (US) | 1976-09-14 | — | — | US | disclosed |
| US-3980700-A | Prostaglandin intermediates and optically active isomers thereof | G. D. SEARLE & CO. (US) | 1976-09-14 | — | — | US | disclosed |
| US-3932467-A | Process for the production of 2β-formyl 3α-protected hydroxy-5-oxocyclopentane-1α-heptanoic acids and esters corresponding | G. D. SEARLE & CO. (US) | 1976-01-13 | — | — | US | disclosed |