Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 10/20 | 0.74 |
| ▸ | MAOB | P27338 | 4/20 | 0.74 |
| ▸ | MAOA | P21397 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.74 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.50 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033131 | 0.89 | PRMT1 (0.62) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL5030461 | 0.89 | PRMT1 (0.64) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL8195760 | 0.89 | NISCH (0.78) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL563160 | 0.86 | NISCH (1.00) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL4206556 | 0.84 | NISCH (0.97) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL5032907 | 0.79 | PRMT1 (0.66) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL5028113 | 0.79 | PRMT1 (0.68) | NISCHMAOBMAOAALDH1A1CYP1A2 | |
| SCHEMBL9189709 | 0.79 | NISCH (0.85) | NISCHMAOB | |
| SCHEMBL24495491 | 0.76 | NISCH (1.00) | NISCHMAOBALDH1A1CYP1A2HPGD | |
| Hydrochloric Acid SCHEMBL7736303 | 0.76 | NISCH (0.58) | NISCHMAOBMAOAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |