Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201681 | 0.87 | MEN1 (0.58) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL28738676 | 0.82 | MAPT (0.59) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL29488257 | 0.80 | MAPT (0.54) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL28738684 | 0.80 | MAPT (0.54) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL2257236 | 0.80 | PARP1 (0.57) | MAPTMEN1POLBKMT2APARP1 | |
| SCHEMBL29839746 | 0.80 | PARP1 (0.57) | MAPTMEN1POLBKMT2APARP1 | |
| SCHEMBL28738671 | 0.79 | MAPT (0.51) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL4936663 | 0.79 | MAPT (0.51) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL28872357 | 0.78 | PARP1 (0.56) | MAPTMEN1POLBKMT2APLA2G1B | |
| SCHEMBL3020634 | 0.78 | PARP1 (0.56) | MAPTMEN1POLBKMT2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063668-A1 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |