SCHEMBL8197041

SCHEMBL8197041

CC(CCSc1nsnc1C1CN2CCCC1C2)CCSc1nsnc1C1CN2CCCC1C2

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 3/20 0.56
CHRM2 P08172 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7818484 0.93 CHRM1 (0.56) CHRM1CHRM2
SCHEMBL7811114 0.88 CHRM1 (0.54) CHRM1CHRM2
SCHEMBL7986264 0.88 CHRM1 (0.54) CHRM1CHRM2
SCHEMBL7818609 0.88 CHRM1 (0.54) CHRM1CHRM2
SCHEMBL7949495 0.88 CHRM1 (0.54) CHRM1CHRM2
SCHEMBL5826272 0.88 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL7949409 0.88 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL7952950 0.88 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL6459621 0.88 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL7988748 0.88 CHRM1 (0.64) CHRM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628041-B1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 2000-07-12 EP claimed
US-5414009-A Cognition activators, analgesics; Alzheimer's disease, glaucoma NOVO NORDISK A/S (DK) 1995-05-09 US claimed
EP-0628041-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-12-14 EP claimed
WO-1993014089-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-07-22 WO claimed
WO-1993014090-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-07-22 WO claimed