Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197833 | 0.88 | GRIA1 (0.34) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL8198097 | 0.88 | MEN1 (0.37) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL8186583 | 0.82 | MEN1 (0.36) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL8505663 | 0.81 | MEN1 (0.33) | GRIA1GRIA2GRIA3GRIA4MEN1 | |
| SCHEMBL8502814 | 0.80 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8186535 | 0.80 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL8197835 | 0.80 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8185988 | 0.80 | GRIA1 (0.36) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8195327 | 0.79 | GRIA1 (0.39) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8368431 | 0.79 | GRIA1 (0.42) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783504-B1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE AS ANTAGONISTS OF AMPA-RECEPTORS | NOVO NORDISK AS (DK) | 2000-03-15 | — | — | EP | claimed |
| EP-0783504-B1 | [1,2,4]TRIAZOLO[4,3-a]QUINOXALINONE DERIVATIVES, THEIR PREPARATION AND USE AS ANTAGONISTS OF AMPA-RECEPTORS | NOVO NORDISK AS (DK) | 2000-03-15 | — | — | EP | disclosed |
| US-6001832-A | [1,2,4]triazolo[4,3-a]quinoxalinone derivatives, their preparation and use | NOVO NORDISKALS (DK) | 1999-12-14 | — | — | US | disclosed |