SCHEMBL8198211

SCHEMBL8198211

CCCCC1(c2cccc(Oc3cc(C(N)Cc4cncn4C)ccc3C#N)c2)CCCCN(C)C1=O

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.70
FNTB P49356 20/20 0.70
PGGT1B P53609 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8156854 0.93 FNTA (0.80) FNTAFNTBPGGT1B
SCHEMBL8186979 0.91 FNTA (0.70) FNTAFNTBPGGT1B
SCHEMBL8195635 0.91 FNTA (0.72) FNTAFNTBPGGT1B
SCHEMBL8199948 0.91 FNTA (0.72) FNTAFNTBPGGT1B
SCHEMBL8186932 0.91 FNTA (0.72) FNTAFNTBPGGT1B
SCHEMBL8197748 0.91 FNTA (0.72) FNTAFNTBPGGT1B
SCHEMBL8236735 0.87 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL8186113 0.87 FNTA (0.69) FNTAFNTBPGGT1B
SCHEMBL8195493 0.86 FNTA (0.66) FNTAFNTBPGGT1B
SCHEMBL8197892 0.85 FNTA (0.68) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000034437-A2 INHIBITORS OF PRENYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 2000-06-15 WO disclosed