Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.54 |
| ▸ | FNTB | P49356 | 11/20 | 0.54 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205645 | 1.00 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL7706173 | 0.95 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7706180 | 0.95 | FNTA (0.51) | FNTAFNTB | |
| SCHEMBL7703362 | 0.94 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7703365 | 0.94 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7703446 | 0.93 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7703452 | 0.93 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL8205752 | 0.89 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL8383788 | 0.89 | FNTA (0.45) | FNTAFNTBPGGT1B | |
| SCHEMBL8213988 | 0.89 | FNTA (0.43) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |