SCHEMBL8199255

SCHEMBL8199255

C=CCOC(=O)C1=C(SCCO)SC2C(C(C)O[Si](C)(C)C(C)(C)C)C(=O)N12

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 8/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1387355 1.00 ELANE (0.41) ELANE
SCHEMBL21667398 0.93 ELANE (0.43) ELANE
SCHEMBL10682598 0.89 ELANE (0.39) ELANE
SCHEMBL8798708 0.86
SCHEMBL9708389 0.85 ELANE (0.39) ELANE
SCHEMBL1388898 0.85 ELANE (0.39) ELANE
SCHEMBL25601234 0.85 ELANE (0.39) ELANE
SCHEMBL22844537 0.85 ELANE (0.39) ELANE
SCHEMBL25608958 0.85 ELANE (0.39) ELANE
SCHEMBL8982847 0.85 ELANE (0.39) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0997466-A1 Novel antimicrobial lactam-quinolones PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) 2000-05-03 EP disclosed
US-5656623-A BACTERICIDES; ANTIBIOTICS THE PROCTER & GAMBLE COMPANY (US) 1997-08-12 US disclosed
US-5648346-A Antimicrobial carbacephem-quinolones THE PROCTER & GAMBLE COMPANY (US) 1997-07-15 US disclosed
US-5646139-A TREATING AND PREVENTING INFECTION THE PROCTER & GAMBLE COMPANY (US) 1997-07-08 US disclosed
US-5637580-A ANTIBIOTICS THE PROCTER & GAMBLE COMPANY (US) 1997-06-10 US disclosed
EP-0366189-A2 Novel antimicrobial lactam-quinolones Norwich Eaton Pharmaceuticals, Inc. (US) 1990-05-02 EP disclosed