SCHEMBL8200006

SCHEMBL8200006

NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
ITGB2 P05107 2/20 0.37
ICAM1 P05362 2/20 0.37
ITGAL P20701 2/20 0.37
CA2 P00918 6/20 0.35
CA1 P00915 4/20 0.35
PTGS1 P23219 1/20 0.35
GSTK1 Q9Y2Q3 1/20 0.35
CTSB P07858 2/20 0.35
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18109901 1.00 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL9755020 1.00 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL901315 0.97 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8717807 0.97 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8720265 0.97 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL5435922 0.97 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8344856 0.97 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8422216 0.97 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL8722676 0.97 ECE1 (0.43) ECE1MEN1KMT2AALDH1A1RAB9A
SCHEMBL15442513 0.97 ECE1 (0.44) ECE1MEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116368233-A Engineered biosynthetic pathway for the production of 4-aminophenylamine by fermentation 齐默尔根公司 2023-06-30 CN disclosed
CN-108289494-B Polypeptides capable of producing glucans with alpha-1, 2 branching and uses thereof 营养与生物科学美国4公司 2022-06-14 CN disclosed
EP-3975702-A1 DOWNY MILDEW RESISTANT SPINACH AND GENES CONFERRING RESISTANCE TO DOWNY MILDEW Enza Zaden Beheer B.V. (NL) 2022-04-06 EP disclosed
CN-108192853-B Method for promoting microbial cells to transport glucose, xylose and arabinose and application of method in fermentation of bio-based products 中国科学院天津工业生物技术研究所 2022-04-05 CN disclosed
CN-112930395-A RNA-targeting fusion protein compositions and methods of use 洛卡纳生物股份有限公司 2021-06-08 CN disclosed
WO-2020239572-A1 DOWNY MILDEW RESISTANT SPINACH AND GENES CONFERRING RESISTANCE TO DOWNY MILDEW ENZA ZADEN BEHEER B.V. (NL) 2020-12-03 WO disclosed
CN-110106187-B ARF gene of rubber tree and coding protein and application thereof 中国热带农业科学院橡胶研究所 2020-11-24 CN disclosed
CN-111793640-A Tobacco plants and methods of using such plants 奥驰亚客户服务公司 2020-10-20 CN disclosed
CN-111094334-A Antibodies and methods for diagnosis and treatment of hepatitis B virus infection 美国卫生与公众服务部 2020-05-01 CN disclosed
CN-110106187-A The ARF gene and its coding albumen of a kind of rubber tree and application 中国热带农业科学院橡胶研究所 2019-08-09 CN disclosed
CN-1362994-A Enzymes of the biosynthetic pathway for the production of triacylglycerol and recombinant DNA molecules encoding these enzymes BASF PLANT SCIENCE GMBH (DE) 2002-08-07 CN disclosed
US-6066318-A Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors G.D. SEARLE & CO. (US) 2000-05-23 US disclosed
CN-1242049-A Multifunctional chimeric hematopoietic receptor agonists SEARLE & CO (US) 2000-01-19 CN disclosed
US-5962315-A VECTOR WITH NUCLEIC ACID WHICH CODES FOR POLYPEPTIDE IMPORTANT IN CELL CYCLE REGULATION; FOR GENETIC ENGINEERING, DIAGNOSIS OF TUMORS, ANTITUMOR AGENTS DANA-FARBER CANCER INSTITUTE (US) 1999-10-05 US disclosed
US-5955258-A USING HOMOLOGOUS AND HETEROLOGOUS PROTEOLYTIC ENZYMES FROM GRAM POSITIVE LACTOBACILLUS TO DISRUPT BACTERIAL CELL IN CULTURE; BACTERICIDES; TO PREVENT FOOD SPOILAGE AND IMPROVING SELF LIFE;FOOD PROCESSING OF CHEESE QUEST INTERNATIONAL B.V. (NL) 1999-09-21 US disclosed
EP-0935663-A2 MULTI-FUNCTIONAL CHIMERIC HEMATOPOIETIC RECEPTOR AGONISTS G.D. SEARLE & CO. (US) 1999-08-18 EP disclosed
CN-1204369-A Multifunctional hematopoietic receptor agonists SEARLE & CO (US) 1999-01-06 CN disclosed
WO-1998017810-A2 MULTI-FUNCTIONAL CHIMERIC HEMATOPOIETIC RECEPTOR AGONISTS G.D. SEARLE & CO. (US) 1998-04-30 WO disclosed
EP-0759998-A1 PROCESS FOR THE LYSIS OF A CULTURE OF LACTIC ACID BACTERIA BY MEANS OF A LYSIN, AND USES OF THE RESULTING LYSED CULTURE QUEST INTERNATIONAL B.V. (NL) 1997-03-05 EP disclosed
WO-1995031561-A1 PROCESS FOR THE LYSIS OF A CULTURE OF LACTIC ACID BACTERIA BY MEANS OF A LYSIN, AND USES OF THE RESULTING LYSED CULTURE QUEST INTERNATIONAL B.V. (NL) 1995-11-23 WO disclosed