Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10301447 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL18826026 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL371668 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL18826032 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL2146038 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL18825900 | 1.00 | HIF1A (0.42) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL18825997 | 0.98 | HIF1A (0.40) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL6819727 | 0.93 | TYR (0.38) | HIF1AEPAS1TYRMAPTALOX15 | |
| SCHEMBL7684833 | 0.92 | F7 (0.48) | HIF1AEPAS1MAPTALOX15BID | |
| SCHEMBL7687682 | 0.91 | HIF1A (0.37) | HIF1AEPAS1TYRMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473911-B | Formylthiophenes and their use in flavour and fragrance compositions | 国际香料和香精公司 | 2021-10-29 | — | — | CN | claimed |
| EP-3371291-B1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2020-02-19 | — | — | EP | claimed |
| EP-3371291-A1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2018-09-12 | — | — | EP | claimed |
| CN-108473911-A | Formylthiophenes and their use in flavour and fragrance compositions | 国际香料和香精公司 | 2018-08-31 | — | — | CN | claimed |
| CN-105294735-B | A kind of phenothiazines organic molecule donor and preparation method thereof | 武汉工程大学 | 2018-03-20 | — | — | CN | claimed |
| WO-2017079368-A1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-05-11 | — | — | WO | claimed |
| CN-105330678-A | Phenothiazine-like electron donor material and preparation method thereof | WUHAN INST TECHNOLOGY | 2016-02-17 | — | — | CN | claimed |
| CN-105294735-A | Phenothiazine organic small molecule donor and preparation method thereof | WUHAN INST TECHNOLOGY | 2016-02-03 | — | — | CN | claimed |
| CN-109438415-B | Non-condensed electron acceptor material, preparation method and organic solar cell constructed by same | 浙江大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-113072533-B | Non-condensed electron acceptor material and organic solar cell constructed by same | 浙江大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-108473911-B | Formylthiophenes and their use in flavour and fragrance compositions | 国际香料和香精公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113072533-A | Non-condensed electron acceptor material and organic solar cell constructed by same | 浙江大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-108997304-B | Alkyl chain thienyl Schiff base and synthetic method thereof | 阜阳师范大学 | 2020-04-17 | — | — | CN | disclosed |
| EP-3371291-B1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2020-02-19 | — | — | EP | disclosed |
| CN-1052224-C | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 2000-05-10 | — | — | CN | disclosed |
| US-5760058-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5656642-A | Peripheral vasodilating agent containing piperidine derivative as active ingredient | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| CN-1104412-A | Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients | OTSUKA PHARMA CO LTD (JP) | 1995-06-28 | — | — | CN | disclosed |
| EP-0650476-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994022826-A1 | PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |