Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | FASN | P49327 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786930 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL5864654 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL5172288 | 1.00 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL11687983 | 0.84 | FASN (0.53) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL3761884 | 0.78 | FASN (0.49) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL1493179 | 0.78 | FASN (0.49) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL11825236 | 0.77 | FASN (0.47) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL5973225 | 0.75 | TDP1 (0.46) | SLC6A2SLC6A4SLC6A3FASNTSHR | |
| SCHEMBL7545254 | 0.75 | FASN (0.46) | SLC6A2SLC6A4SLC6A3FASNTAAR1 | |
| SCHEMBL5973222 | 0.75 | TDP1 (0.46) | SLC6A2SLC6A4SLC6A3FASNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052257-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-3-AMINO-1,2-EPOXY COMPOUNDS | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-15 | — | — | EP | disclosed |