Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706725 | 0.92 | HPGD (0.51) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL6251738 | 0.91 | HRH3 (0.49) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL6850513 | 0.91 | HPGD (0.57) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL4572676 | 0.89 | HRH1 (0.53) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL38662956 | 0.88 | HRH1 (0.46) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL28159880 | 0.88 | SLC6A4 (0.47) | HRH1HRH3MEN1HPGDKMT2A | |
| SCHEMBL18505947 | 0.83 | HRH1 (0.48) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL4572675 | 0.82 | HPGD (0.52) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL4572678 | 0.82 | HRH1 (0.50) | HRH1HRH3LMNATAAR1ALDH1A1 | |
| SCHEMBL4572677 | 0.80 | HPGD (0.55) | HRH1HRH3MEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043227-A | C11 carbamates of macrolide antibacterials | PFIZER INC. (US) | 2000-03-28 | — | — | US | disclosed |