Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8194936 | 0.93 | MEN1 (0.45) | ARSIGMAR1MEN1KMT2APDE4A | |
| SCHEMBL8195461 | 0.81 | MEN1 (0.46) | MEN1KMT2AL3MBTL1HTR1BCMA1 | |
| SCHEMBL8186964 | 0.81 | MEN1 (0.46) | MEN1KMT2AL3MBTL1HTR1BCMA1 | |
| SCHEMBL8199859 | 0.81 | MEN1 (0.46) | MEN1KMT2AL3MBTL1HTR1BCMA1 | |
| SCHEMBL8198385 | 0.81 | MEN1 (0.46) | MEN1KMT2AHTR1BCMA1LMNA | |
| SCHEMBL8195469 | 0.80 | MEN1 (0.45) | MEN1KMT2AL3MBTL1HTR1BCMA1 | |
| SCHEMBL8195370 | 0.78 | EED (0.44) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL6730275 | 0.78 | CYP1A2 (0.41) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL8194932 | 0.76 | EED (0.42) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL622589 | 0.72 | PDE4A (0.46) | ARSIGMAR1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034437-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-06-15 | — | — | WO | disclosed |