⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790 | 0.82 | — | — | |
| SCHEMBL13361150 | 0.75 | KCNH2 (0.38) | — | |
| SCHEMBL16021554 | 0.74 | — | — | |
| SCHEMBL3291349 | 0.73 | — | — | |
| SCHEMBL14637378 | 0.73 | — | — | |
| SCHEMBL23684368 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL25323764 | 0.71 | — | — | |
| SCHEMBL11312644 | 0.71 | — | — | |
| SCHEMBL23708983 | 0.70 | — | — | |
| SCHEMBL24896362 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722316-B1 | NEW EMULSION FORMULATION | ASTRA AB (SE) | 2000-01-26 | — | — | EP | claimed |
| US-5843465-A | Emulsion formulation | ASTRA AKTIEBOLAG (SE) | 1998-12-01 | — | — | US | claimed |
| EP-0722316-A1 | NEW EMULSION FORMULATION | Astra Aktiebolag (SE) | 1996-07-24 | — | — | EP | claimed |
| WO-1995009609-A1 | NEW EMULSION FORMULATION | ASTRA AKTIEBOLAG (SE) | 1995-04-13 | — | — | WO | claimed |
| CN-110183435-B | Oxazole drug molecule for hospital sterilization and preparation method thereof | 河南科技大学第一附属医院 | 2020-02-07 | — | — | CN | disclosed |
| CN-104817549-A | Oxazole compound with anti-fungal activity, preparation method of oxazole compound and application of oxazole compound | UNIV HENAN NORMAL | 2015-08-05 | — | — | CN | disclosed |
| CN-103058946-A | Preparation method for 2,5-disubstituted oxazole derivative | UNIV ZHEJIANG TECHNOLOGY | 2013-04-24 | — | — | CN | disclosed |
| EP-0722316-B1 | NEW EMULSION FORMULATION | ASTRA AB (SE) | 2000-01-26 | — | — | EP | disclosed |
| US-5843465-A | Emulsion formulation | ASTRA AKTIEBOLAG (SE) | 1998-12-01 | — | — | US | disclosed |
| US-5660837-A | ADDING STABILIZING SURFACTANT OR SURFACTANT DRUG, THEN HIGH PRESSURE HOMOGENIZING | ASTRA AKTIEBOLAG (SE) | 1997-08-26 | — | — | US | disclosed |
| EP-0722316-A1 | NEW EMULSION FORMULATION | Astra Aktiebolag (SE) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009609-A1 | NEW EMULSION FORMULATION | ASTRA AKTIEBOLAG (SE) | 1995-04-13 | — | — | WO | disclosed |
| US-4080459-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-03-21 | — | — | US | disclosed |
| US-4070475-A | THIOALKYL-, AMINOALKYL-, AND OXYALKYL- SUBSTITUTED GUANIDINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1978-01-24 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-4013769-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |