Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193484 | 0.93 | KDM4E (0.33) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8193819 | 0.90 | KDM4E (0.35) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8201864 | 0.90 | KDM4E (0.35) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8204062 | 0.88 | KDM4E (0.36) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8908783 | 0.85 | KDM4E (0.49) | KDM4EPOLBKCNH2 | |
| SCHEMBL8201672 | 0.84 | KDM4E (0.35) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8201013 | 0.83 | KDM4E (0.34) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9232358 | 0.81 | KDM4E (0.40) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL8204059 | 0.81 | CACNA1F (0.36) | KDM4ECACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9234627 | 0.81 | CACNA1F (0.51) | KDM4ECACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682030-B1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-0682030-A1 | 8-Amino-10(azabicycloalkyl)-pyrido[1,2,3-d,e] [1,3,4] benzoxadiazine derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |