Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204124 | 0.91 | TACR1 (0.34) | TACR1 | |
| SCHEMBL8194454 | 0.82 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8193750 | 0.82 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8194349 | 0.81 | TACR1 (0.37) | TACR1 | |
| SCHEMBL8204408 | 0.74 | TACR1 (0.37) | TACR1 | |
| SCHEMBL8201260 | 0.74 | TACR1 (0.37) | TACR1 | |
| SCHEMBL8718133 | 0.72 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8204411 | 0.72 | TACR1 (0.38) | TACR1 | |
| SCHEMBL8201999 | 0.72 | GRIN2D (0.36) | TACR1 | |
| SCHEMBL8202011 | 0.71 | TACR1 (0.36) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080740-A | Spiro-ketal derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2000-06-27 | — | — | US | claimed |
| US-6080740-A | Spiro-ketal derivatives and their use as therapeutic agents | MERCK SHARP & DOHME LTD. (GB) | 2000-06-27 | — | — | US | disclosed |