Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.69 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094123 | 0.85 | NISCH (0.67) | NISCHMAOB | |
| SCHEMBL29446967 | 0.85 | NISCH (0.67) | NISCHMAOB | |
| Hydrochloric Acid SCHEMBL27888413 | 0.84 | NISCH (0.65) | NISCHMAOB | |
| Hydrochloric Acid SCHEMBL29755905 | 0.84 | NISCH (0.65) | NISCHMAOB | |
| Hydrochloric Acid SCHEMBL1143198 | 0.83 | NISCH (0.63) | NISCHMAOB | |
| SCHEMBL8204316 | 0.82 | NISCH (0.74) | NISCHADRA2AADRA2BADRA2CMAOB | |
| SCHEMBL8195024 | 0.81 | NISCH (0.67) | NISCHMAOB | |
| SCHEMBL9579892 | 0.80 | NISCH (0.81) | NISCH | |
| SCHEMBL8201878 | 0.80 | NISCH (0.51) | NISCHADRA2AADRA2BADRA2CMAOB | |
| SCHEMBL8204363 | 0.78 | NISCH (0.76) | NISCHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |