Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 10/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459669 | 0.90 | MEN1 (0.53) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10640678 | 0.86 | CYP3A4 (0.49) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9632700 | 0.86 | CYP3A4 (0.49) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL19242621 | 0.84 | MAPT (0.55) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10642092 | 0.84 | CYP3A4 (0.50) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10640410 | 0.84 | CYP3A4 (0.50) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL9631948 | 0.84 | CYP3A4 (0.47) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL8205210 | 0.83 | MAPT (0.52) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10638804 | 0.83 | MEN1 (0.44) | MAPTCYP3A4MEN1ALDH1A1TP53 | |
| SCHEMBL10636160 | 0.82 | CYP3A4 (0.52) | MAPTCYP3A4MEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000273041-A | INHIBITOR OF NEUROCYTE APOPTOSIS WITH GLUTAMIC ACID CYTOTOXICITY | SANKYO CO LTD | 2000-10-03 | — | — | JP | disclosed |