Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14459762 | 1.00 | CYP1A2 (0.60) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL24825 | 1.00 | CYP1A2 (0.60) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5434321 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL8337559 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5443335 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5436210 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL26641 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5441593 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5434325 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR | |
| SCHEMBL5441592 | 0.89 | CYP1A2 (0.64) | CYP1A2ALDH1A1USP2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103932-A | USEFUL AS AGENTS IN THE TREATMENT OF EPILEPSY, FAINTNESS ATTACKS, HYPOKINESIA, CRANIAL DISORDERS, NEURODEGENERATIVE DISORDERS, DEPRESSION, ANXIETY, PANIC, PAIN, AND NEUROPATHOLOGICAL DISORDERS | WARNER-LAMBERT COMPANY (US) | 2000-08-15 | — | — | US | disclosed |