SCHEMBL8202152

SCHEMBL8202152

CCc1cc(OC)cc2nc(-c3cccnc3)oc(=O)c12

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.56
F2 P00734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263349 0.78 ELANE (0.67) ELANE
SCHEMBL17554129 0.77 ELANE (0.57) ELANEF2
SCHEMBL12897785 0.77 ELANE (0.80) ELANE
SCHEMBL8215130 0.77 ELANE (0.65) ELANE
SCHEMBL12898037 0.76 ELANE (0.66) ELANE
SCHEMBL12897714 0.75 ELANE (0.65) ELANE
SCHEMBL12897715 0.74 ELANE (0.69) ELANE
SCHEMBL8213753 0.74 ELANE (0.69) ELANE
SCHEMBL12897784 0.74 ELANE (0.67) ELANE
SCHEMBL8212788 0.74 ELANE (0.86) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008036379-A2 SERINE HYDROLASE INHIBITORS ACTIVX BIOSCIENCES, INC. (US) 2008-03-27 WO disclosed