Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.54 |
| ▸ | FLT1 | P17948 | 10/20 | 0.54 |
| ▸ | RET | P07949 | 7/20 | 0.54 |
| ▸ | KIF5B | P33176 | 7/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.54 |
| ▸ | EGFR | P00533 | 6/20 | 0.52 |
| ▸ | FLT4 | P35916 | 4/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455756 | 0.85 | KDR (0.54) | KDRFLT1RETKIF5BFGFR1 | |
| SCHEMBL7211052 | 0.84 | EGFR (0.59) | KDRFLT1RETKIF5BFGFR1 | |
| Hydrochloric Acid SCHEMBL7454404 | 0.83 | EGFR (0.58) | KDRFLT1RETKIF5BFGFR1 | |
| SCHEMBL7454958 | 0.81 | KDR (0.67) | KDRFLT1RETKIF5BFGFR1 | |
| SCHEMBL7209561 | 0.80 | KDR (0.67) | KDRFLT1RETKIF5BFGFR1 | |
| SCHEMBL7452337 | 0.79 | KDR (0.56) | KDRFLT1RETKIF5BFGFR1 | |
| Hydrochloric Acid SCHEMBL7448336 | 0.79 | KDR (0.66) | KDRFLT1RETKIF5BFGFR1 | |
| Hydrochloric Acid SCHEMBL7214453 | 0.78 | KDR (0.59) | KDRFLT1RETKIF5BFGFR1 | |
| SCHEMBL7209629 | 0.76 | KDR (0.79) | KDRFLT1RETKIF5BFGFR1 | |
| Hydrochloric Acid SCHEMBL7209962 | 0.76 | KDR (0.54) | KDRFLT1RETKIF5BFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071921-A | Chemical compounds | ZENECA LIMITED (GB) | 2000-06-06 | — | — | US | disclosed |