Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209765 | 1.00 | GSK3B (0.36) | GSK3BDYRK1ASCN9ALCKTGFBR1 | |
| SCHEMBL4727370 | 0.89 | SCN9A (0.36) | GSK3BDYRK1ASCN9ALCKTGFBR1 | |
| SCHEMBL2257599 | 0.88 | JAK3 (0.35) | GSK3BDYRK1ASCN9ALCKBRD4 | |
| SCHEMBL2257605 | 0.88 | JAK3 (0.35) | GSK3BDYRK1ASCN9ALCKBRD4 | |
| SCHEMBL2260109 | 0.88 | JAK3 (0.35) | GSK3BDYRK1ASCN9ALCKBRD4 | |
| SCHEMBL2261585 | 0.88 | JAK3 (0.35) | GSK3BDYRK1ASCN9ALCKBRD4 | |
| SCHEMBL2259978 | 0.88 | JAK3 (0.35) | GSK3BDYRK1ASCN9ALCKBRD4 | |
| SCHEMBL2600843 | 0.80 | SSTR4 (0.35) | GSK3BDYRK1ASCN9ALCKSSTR4 | |
| SCHEMBL2115673 | 0.80 | SSTR4 (0.35) | GSK3BDYRK1ASCN9ALCKSSTR4 | |
| SCHEMBL2785572 | 0.80 | SSTR4 (0.35) | GSK3BDYRK1ASCN9ALCKSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008042353-A1 | POTENT AND HIGHLY SELECTIVE HETEROAROMATIC INHIBITORS OF NEURONAL NITRIC OXIDE SYNTHASE | NORTHWESTERN UNIVERSITY (US) | 2008-04-10 | — | — | WO | disclosed |