SCHEMBL8202377

SCHEMBL8202377

CNCCNc1ncccc1-c1nc2cccc(C)c2c(=O)o1

nearest known ligand 0.78

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ELANE P08246 19/20 0.78
C1R P00736 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8210571 0.88 ELANE (1.00) ELANEC1R
SCHEMBL8209587 0.88 ELANE (0.75) ELANEC1R
SCHEMBL12924581 0.87 ELANE (0.74) ELANEC1R
SCHEMBL8212983 0.83 ELANE (1.00) ELANEC1R
SCHEMBL8210285 0.79 ELANE (1.00) ELANEC1R
SCHEMBL12897305 0.77 ELANE (0.81) ELANEC1R
SCHEMBL913650 0.77 ELANE (0.77) ELANEC1R
SCHEMBL8215255 0.77 ELANE (0.77) ELANEC1R
SCHEMBL8006834 0.76 C1R (0.81) ELANEC1R
SCHEMBL8213595 0.75 ELANE (0.73) ELANEC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008036379-A2 SERINE HYDROLASE INHIBITORS ACTIVX BIOSCIENCES, INC. (US) 2008-03-27 WO disclosed