Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 20/20 | 0.90 |
| ▸ | F10 | P00742 | 19/20 | 0.90 |
| ▸ | F2 | P00734 | 12/20 | 0.90 |
| ▸ | PLG | P00747 | 12/20 | 0.90 |
| ▸ | PLAU | P00749 | 12/20 | 0.90 |
| ▸ | TMPRSS6 | Q8IU80 | 7/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196664 | 0.95 | ST14 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL6874294 | 0.91 | F10 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL19309734 | 0.90 | ST14 (0.86) | ST14F10F2PLGPLAU | |
| SCHEMBL12998786 | 0.90 | ST14 (0.86) | ST14F10F2PLGPLAU | |
| SCHEMBL8196584 | 0.90 | F10 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL8190331 | 0.89 | F10 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL8201054 | 0.89 | F10 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL12998731 | 0.88 | F10 (1.00) | ST14F10F2PLGPLAU | |
| SCHEMBL14669479 | 0.88 | F10 (0.92) | ST14F10F2PLGPLAU | |
| SCHEMBL8196581 | 0.87 | ST14 (1.00) | ST14F10F2PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107176-A1 | META-SUBSTITUTED PHENYL SULFONYL AMIDES OF SECONDARY AMINO ACID AMIDES, THE PRODUCTION THEREOF, AND USE THEREOF AS MATRIPTASE INHIBITORS | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2008-09-12 | — | — | WO | disclosed |