SCHEMBL8202813

SCHEMBL8202813

C(CCSc1nsnc1C1CN2CCC1C2)CSc1nsnc1C1CN2CCC1CC2

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8197649 0.96 CHRM2 (0.58) CHRM2
SCHEMBL9540628 0.96 CHRM2 (0.58) CHRM2
SCHEMBL8195856 0.96 CHRM1 (0.54)
SCHEMBL8196556 0.95 CHRM1 (0.56) CHRM2
Hydrochloric Acid SCHEMBL8200001 0.94 CHRM1 (0.53)
SCHEMBL9544481 0.92 CHRM1 (0.58) CHRM2
SCHEMBL8189296 0.92 CHRM1 (0.58) CHRM2
SCHEMBL7810781 0.91 CHRM1 (0.60)
SCHEMBL7818811 0.90 CHRM1 (0.60)
SCHEMBL7819640 0.90 CHRM1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628041-B1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK AS (DK) 2000-07-12 EP disclosed
US-5977129-A ALZHEIMER'S DISEASE NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
US-5414009-A Cognition activators, analgesics; Alzheimer's disease, glaucoma NOVO NORDISK A/S (DK) 1995-05-09 US disclosed
EP-0628041-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-12-14 EP disclosed
WO-1993014089-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-07-22 WO disclosed
WO-1993014090-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1993-07-22 WO disclosed