Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN2 | P17655 | 7/20 | 0.75 |
| ▸ | MMP2 | P08253 | 11/20 | 0.45 |
| ▸ | MMP7 | P09237 | 11/20 | 0.45 |
| ▸ | MMP3 | P08254 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 9/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PROC | P04070 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208871 | 0.92 | CAPN2 (0.74) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL930019 | 0.89 | CAPN2 (0.74) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL8208872 | 0.86 | CAPN2 (1.00) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL930611 | 0.86 | CAPN2 (1.00) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL930382 | 0.84 | CAPN2 (0.76) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL931644 | 0.83 | CAPN2 (1.00) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL931065 | 0.80 | CAPN2 (0.58) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL15869981 | 0.80 | CAPN2 (0.61) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL930579 | 0.79 | CAPN2 (1.00) | CAPN2MMP2MMP7MMP3MMP1 | |
| SCHEMBL15869976 | 0.79 | CAPN2 (0.59) | CAPN2MMP2MMP7MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048121-A2 | MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF | LINCOLN UNIVERSITY (NZ) | 2008-04-24 | — | — | WO | disclosed |