Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN2 | P17655 | 10/20 | 0.73 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930579 | 0.84 | CAPN2 (1.00) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL8208872 | 0.74 | CAPN2 (1.00) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL930611 | 0.74 | CAPN2 (1.00) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL931644 | 0.73 | CAPN2 (1.00) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL930382 | 0.71 | CAPN2 (0.76) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL12943163 | 0.69 | CAPN2 (1.00) | CAPN2CPB2 | |
| SCHEMBL15654382 | 0.68 | CAPN2 (0.63) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL931991 | 0.67 | CAPN2 (0.77) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL12943087 | 0.66 | CAPN2 (0.57) | CAPN2CPB2MMP1MMP2MMP3 | |
| SCHEMBL12943105 | 0.64 | CAPN2 (0.56) | CAPN2CPB2MMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008048121-A2 | MACROCYCLIC CYSTEINE PROTEASE INHIBITORS AND COMPOSITIONS THEREOF | LINCOLN UNIVERSITY (NZ) | 2008-04-24 | — | — | WO | disclosed |